Chronic rumbling erosive gastritis with bile reflux for 20 days of medication is not good, may be the role of the drug is weakened or aggravation of the symptoms and so on, it is recommended to change the drug treatment, or anti-reflux, general treatment. 1. Combined use of drugs: the use of a single type of drugs, in the acidic environment can not play the original effect, resulting in symptoms do not improve, should be used to inhibit the secretion of gastric acid, protect the gastric mucosa of the drugs, commonly used drugs such as omeprazole, bismuth potassium citrate, and so on. 2. Anti-reflux: If the symptoms worsen, acid-suppressing drugs and gastric mucosa protectors, such as omeprazole, bismuth potassium citrate, etc., can be used for treatment. 3. General treatment: regulate the diet, do not eat cold, spicy and irritating food, quit smoking and drinking, and ensure enough sleep. Take medication according to the doctor’s prescription. If the medication is ineffective for a long time, it is recommended to go to the hospital in time to find out the cause.