Women present with a positive HPV59 high-risk type, which is a high-risk factor for cervical cancer. Usually it is contracted through sexual intercourse, for example, men with HPV infection can transmit it directly to women through sexual intercourse. In addition, we can also indirectly get infected with this virus by contacting sanitary ware in public sanitary places, such as toilets. Many women can turn negative within two years, but only a small percentage of women can be persistently positive. Then HPV high-risk persistent positive is a high-risk factor for cervical cancer, which can trigger the epithelial lesions in the squamous junction area of the cervix in women. For example, low grade cervical intraepithelial neoplasia occurs first, and then progresses to high grade. Once we have a positive high risk, we have to do TCT to rule out the possibility of cervical intraepithelial neoplasia. For a simple HPV59 high-risk positive, we can first observe clinically and then recheck once in six months to a year to see if it can turn negative naturally.