For patients with chronic colitis with celiac disease can be cured, need to analyze the specific situation, most of the genetic, immune factors caused by chronic colitis patients difficult to cure, can only control the symptoms, but the infection caused by chronic colitis patients there is a greater possibility of healing, the specifics need to be further colonoscopy to identify the cause of the disease. For chronic colitis caused by infection, generally in the active anti-infection treatment, can play an effective role in the treatment of chronic colitis with celiac disease, the most common drugs are ciprofloxacin, metronidazole and other antibiotics; the vast majority of patients in the elimination of pathogens, can be cured. However, for genetic, immune-induced chronic colitis, most of these patients are generally very difficult to cure, in the current clinical situation, only through the use of levocetirizine and other antihistamines to control the patient’s symptoms and try to improve the patient’s quality of life. Although most of the chronic colitis can not be cured, but through active treatment, can effectively control the symptoms, improve the patient’s quality of life, the patient should actively cooperate with the doctor’s treatment, to avoid further development and deterioration of the condition. Drugs should be used under the guidance of a doctor.