High D-dimer does not necessarily indicate tumor spread, and there is no necessary causal relationship between the two.
D-dimer is a test of coagulation function, and its elevation generally suggests the existence of hypercoagulability and hyperfibrinolysis in the body, which is mostly seen in some thrombotic diseases, such as myocardial infarction, cerebral infarction, pulmonary embolism, etc., as well as some serious infections, tumors, or disseminated intravascular coagulation, etc., which may also show elevated levels of D-dimer.
Elevated D-dimer levels represent possible thrombosis in the vascular circulatory system and are a sign of acute thrombosis. When the fibrinolytic system is hyperactive, it breaks down thrombus fragments to form D-dimer. D-dimer represents a hyperactive fibrinolytic system in the body and is also an indicator of the coagulation mechanism.
In addition, D-dimer can be elevated throughout pregnancy, but not abnormally so. If it is abnormally elevated, it represents another disease that must be treated. Therefore, if an abnormally elevated D-dimer is present in the clinic, it is important to go to a regular hospital for diagnosis and treatment in order to prevent more serious consequences.