Male breast enlargement is known as gynecomastia, and its main symptoms can be seen in men with bilateral or unilateral breast enlargement, which may be accompanied by tenderness and nipple overflow. Clinical treatment includes medication and surgery. 1. Medication: The specific medication program needs to be chosen according to the patient’s specific condition. Patients can take anti-estrogenic drugs such as clomiphene and tamoxifen as prescribed by the doctor; aromatase inhibitors such as letrozole and anastrozole can inhibit the conversion of androgens to estrogens. 2. Surgery: When the symptoms continue to be unrelieved, pain is obvious, and there is nipple overflow, cancer may need surgical treatment, such as liposuction after circumareolar mastopexy, lumpectomy, minimally invasive rotary excision and other ways. Generally, most men with breast enlargement can get better without treatment, but there are clear causes of breast enlargement, which can be eliminated by removing the causes. If breast discomfort occurs, you should go to the hospital in time and undergo relevant hospital examinations to clarify the cause of the disease and actively cooperate with the doctor’s treatment.