There are two possibilities for small bumps near the nipple with pain and discomfort. First, the skin near the nipple is rich in sebaceous glands, that is, Montgomery’s nodes, which play a role in moisturizing the nipple and the local skin through the secretion of oil, when it is combined with the infection, it can be swollen and painful and the surrounding skin is red and swollen; when the symptom is mild, roxithromycin ointment should be given to smear on the affected area and pay attention to the dryness of the local area and cleanliness; if the infection is further aggravated, then it is often necessary to carry out surgical treatment; second, folliculitis, which is acute purulent infective lesions in hair follicle tissues. Secondly, folliculitis is an acute purulent infection of the hair follicle tissue, the clinical manifestation of the hair follicle is swollen and painful, and the local pus or fluid may appear, can be given to the vitality of iodine local disinfection, and apply the Bactrim ointment, the symptom can be relieved. In conclusion, when there are small bumps near the nipple with pain, you should go to the breast surgery or general surgery department of regular hospitals in time to clarify the nature of the lesion, so as to achieve early detection and treatment of the disease, and avoid delaying the condition.