Characteristics of the accelerated phase of chronic leukemia

The accelerated phase of chronic leukemia has some of the symptoms of the chronic phase, such as anemia, fatigue, bleeding, and infection, which are significantly worse than before. Identification is based on laboratory tests, which reveal that more than 20% of the blood is basophilic, while the proportion of primitive granulocytes in the bone marrow reaches 10-19%. In addition to chromosomal abnormalities of chromosomes 9 and 22, other chromosomal abnormalities are detected by monitoring, and a diagnosis of accelerated phase is made when there is a sudden drop or significant increase in the number of white blood cells or a significant drop or significant increase in platelets during the course of treatment, in spite of the use of very effective medication, to reach one of these indicators. For the manifestation of accelerated stage, many cases are not based on the patient’s own feeling, if there is obvious feeling, it may have entered the acute stage, the condition in the accelerated stage, timely treatment, there is still a possibility of complete treatment of the cure, but once not timely control, the progression to the acute stage and then go to control it may be relatively more troublesome, just rely on the feeling can not be felt whether it is entering the accelerated stage It is impossible to feel whether the disease has entered the accelerated stage just by feeling, but we must rely on the results of blood test and bone puncture test to determine whether the disease has entered the accelerated stage or not.