Nodular goiter does not belong to simple goiter and there is a difference between the two diseases. 1. Simple goiter: Most of the patients are caused by iodine deficiency, genetic factors or environmental factors. Patients are asymptomatic in the early stage, but in the middle and late stage, they may have enlarged thyroid gland, difficulty in swallowing, hoarse voice, etc. It is recommended to consult a doctor in time. 2. Nodular goiter: nodular goiter is also known as adenomatous goiter, which is mostly caused by iodine deficiency, goiter-causing substances, iodine overdose, enzyme deficiency, genetic factors and other problems. In the early stages of the disease, there are no typical symptoms, but in the later stages of the disease, there is significant neck pain or pressure. Regardless of whether the patient has nodular goiter or simple goiter, he or she should go to the local hospital in time for relevant examination and early detection of the problem and early treatment.