The normal reference range for uric acid varies between men and women. Normally, a male patient’s blood uric acid concentration of 398 μmol/L is within the normal reference range and is normal, but a female patient’s blood uric acid concentration of 398 μmol/L is higher than the upper limit of the normal reference range and is abnormal. Due to the different levels of sex hormones in men and women, and estrogen can have a certain effect on the blood uric acid value, so there is a difference between the normal uric acid level of male and female patients, adult male blood uric acid concentration reference range of 150 ~ 416 μmol / L, and adult female blood uric acid concentration reference range of 89 ~ 357 μmol / L. Therefore, if a male patient’s blood uric acid concentration of 398μmol/L is within the normal reference range, and if the patient is a woman, the value is higher than the upper limit of the normal reference range, which is abnormal, and need to be adjusted according to the specific conditions under the guidance of the doctor to dietary adjustments or lifestyle changes, and other therapeutic measures, and can be given to lower the uric acid medication, if necessary. It is recommended that patients with elevated blood uric acid go to the hospital in a timely manner, under the guidance of a doctor to standardize the treatment, so as not to delay the condition.