The cost of chemotherapy for rectal cancer T3N0M0 usually ranges from a few thousand dollars to tens of thousands of dollars. The cost of one chemotherapy session for rectal cancer T3N0M0 mainly depends on factors such as the choice of chemotherapy regimen and the adverse reactions after chemotherapy. There is a big difference in the types of drugs in different chemotherapy programs, and there is also a big difference in the prices of different manufacturers of drugs (such as imported drugs and domestic drugs), and the general price fluctuates between a few thousand dollars to tens of thousands of dollars, so it is recommended to refer to local hospitals for the specific price. In addition, mild or serious adverse reactions are inevitable in the process of chemotherapy, if there are mild adverse reactions, the treatment cost is less; if there are serious adverse reactions, the treatment cost for the adverse reactions is higher. Rectal cancer patients are recommended to consult doctors in time and cooperate with them for active treatment to prolong the survival period and improve the prognosis.