Young children’s glans pain with foreign matter may be due to warts, penile cancer, pearly papules and other causes. 1. Condyloma acuminatum: It is mainly caused by human papillomavirus infection. Pimples, plaques, papillae or cauliflower-like superfluous organisms may appear on the glans of young children, and a few patients may have symptoms such as foreign body sensation, burning pain and itching. 2. Penile cancer: it is a kind of malignant tumor occurring in male penile area, and its exact cause is still unclear, which may be related to factors such as prepuce, prepuce too long, HPV infection and so on. Patients may have symptoms such as penile swelling, penile breakage and pain, which can cause the phenomenon of young children’s glans pain with foreign body. 3. Pearly papules: mainly caused by inadequate personal hygiene and cleanliness, long foreskin, infection and other reasons. The patient’s coronal edge of the penis and the coronal groove can appear pearly, translucent papules, when accompanied by inflammation, the patient may experience pain. It is recommended that young children with glans pain, accompanied by foreign bodies go to the hospital in a timely manner, do the relevant examination to clarify the cause of the disease, follow the doctor’s instructions for treatment, to avoid delaying the condition.