The ulceration and bleeding of advanced breast cancer necessitates chemotherapy as tolerated by the body. Ulceration and bleeding of advanced breast cancer lesions occur in addition to local treatment. Advanced breast cancer is mainly treated with non-surgical methods such as chemotherapy, targeted therapy and endocrine therapy. Therefore, chemotherapy and other treatments are necessary to prolong the survival period and improve the quality of life as long as the body can tolerate them. Therefore, patients are advised not to give up the chance of treatment and should actively cooperate with doctors to standardize treatment to avoid aggravation of the condition.