Low fever in the early stage of malignant tumors is characterized by a body temperature generally around 38℃, rarely exceeding 38.5℃, which is a kind of non-infectious fever, not accompanied by symptoms of infection such as chills and chills. Fever in early stage of malignant tumor is characterized by persistent low-grade fever, body temperature is usually not more than 38.5 ℃, often appearing in the afternoon low-grade fever, and the fever type may be irregular fever, flaccid fever or auditory fever, etc.. Since malignant tumor hypothermia is not due to fever caused by a pyrogen released by the infecting pathogen, fever-producing symptoms such as chills and chills usually do not occur, and it is not sensitive to anti-infective treatment. Some malignant tumors release inflammatory mediators or substances such as TNF (tumor necrosis factor) during growth, causing febrile symptoms, which is called tumor fever. After diagnosis of malignant tumor, the best treatment is to actively carry out surgical treatment, chemotherapy, radiotherapy, targeted therapy and other comprehensive anti-cancer treatment, purely for the treatment of fever can not solve the cause of the disease, only anti-cancer treatment, malignant tumor-induced hypothermia is likely to get better.