Yellow spots appearing on the white of the patient’s eyes may be caused by hyperpigmentation, blepharospasm, jaundice and other reasons. 1. Hyperpigmentation: yellow spots on the whites of the eyes may be caused by conjunctival hyperpigmentation, which is a relatively common clinical manifestation, usually not accompanied by other discomforts, and does not require special treatment. 2. Blepharospasm: Blepharospasm may be caused by age increase, wind and sun exposure, chemical stimulation, etc., which causes vitellogenic degeneration of subgloboconjunctival tissues, resulting in the formation of conjunctival and subconjunctival tissue hyperplasia, leading to yellow spots on the whites of the eyes of the patients. 3. Jaundice: due to the bilirubin metabolism disorder in the patient’s body, causing jaundice due to the increase of bilirubin concentration in the serum, resulting in sclera yellowing, so the patient can also show the yellowing of the whites of the eyes. It is recommended that patients with yellow spots on the whites of the eyes go to the hospital in time to assess their condition and follow the doctor’s instructions for treatment.