High bilirubin and normal bilirubin are not enough to determine the severity of the disease, and further imaging and histology are needed to clarify the diagnosis. In clinical practice, serum total bilirubin, conjugated bilirubin, unconjugated bilirubin, urinary bilirubin and urobilinogen are often tested to diagnose the presence or absence of hemolysis and to determine the functional status of the hepatic and biliary systems in bile pigment metabolism. In liver function tests, the three bilirubin tests often include direct bilirubin, indirect bilirubin and total bilirubin. Increased total bilirubin, direct bilirubin and indirect bilirubin are usually seen in acute jaundice hepatitis, chronic active hepatitis, cirrhosis and toxic hepatitis. Increased bilirubin and normal liver function parameters may indicate the presence of fatty liver, alcoholic liver and related diseases. At this time, it is necessary to continue to observe whether there are abnormalities in urine and stool, whether there is painless jaundice or accompanied by itching of the skin, etc. It is necessary to continue to clarify the diagnosis through imaging and tumor markers to identify possible tumors, stones and other diseases.