The difference between type 1 diabetes and type 2 diabetes is mainly from the following aspects: 1. The age of onset, type 1 diabetes usually develops in adolescents, while type 2 diabetes tends to develop in adults, commonly in people over 40 years old. 2. In terms of treatment, type 1 diabetes requires lifelong treatment with insulin because of the severe lack of insulin in the body, while type 2 diabetes can be treated with oral medication at the beginning.