Facial oil secretion pore blockage is common in seborrheic dermatitis, acne, rosacea and other diseases, need to be clearly diagnosed, for the specific disease, treatment, usually after the disease treatment, facial oil secretion pore blockage symptoms will also be reduced. 1. seborrheic dermatitis: combined with fungal infections can be used topical antifungal drugs, such as miconazole, ketoconazole, etc., to destroy the fungus, treat the cause of the disease, reduce the symptoms; inflammation is more serious lesions, can be used topical glucocorticosteroid treatment, such as hydrocortisone cream, mometasone furoate cream, etc., to improve the symptoms; but also topical tacrolimus ointment. 2. Acne: Topical benzoyl peroxide can be used for anti-inflammatory, pimple dissolving and exfoliating treatment; topical retinoids, such as isotretinoin and retinoic acid ointment, can also be used to exfoliate and reduce pore clogging; for those with obvious inflammation, oral antibiotic treatment, such as minocycline and doxycycline can be used. 3. Rosacea: This disease can lead to sebum secretion exuberant pore clogging, mostly associated with mite infection, can be used externally antibiotics, such as metronidazole, clindamycin, etc., to control the infection; inflammation is more serious, but also need to take oral antibiotic treatment, such as doxycycline. It is recommended that patients go to the regular hospital dermatology consultation, under the guidance of the doctor to clarify the diagnosis, reasonable medication treatment, not blindly self-medication.