Modern medicine tells us that the key to curing gastric ulcers, duodenal ulcers and gastritis is to find out if there is H. pylori infection. Once this culprit is identified, the right treatment plan can be adopted, focusing on “firepower” to fight the war of annihilation – eradication treatment. To detect the presence of H. pylori in the patient’s stomach, blood sampling, gastroscopy sampling and breath sampling are generally used to detect three methods. 1, blood sampling test that the use of blood sampling methods to detect the level of antibodies to H. pylori in the serum. Because the H. pylori infection, the body can produce the corresponding antibodies, so that the test results are positive, but generally takes several months and a half to be positive, so the early stage of H. pylori infection for the test, the test results often appear false negative, so that patients lose the best time for treatment. In addition, even if H. pylori is eradicated, the antibody declines slowly and patients often lose the best opportunity for treatment. But the antibodies fall slowly, patients often need 1-2 years to turn negative, which will inevitably make the cured long-term carry the “positive” black pot and accept the redundant treatment. 2, gastroscopy sampling test can be done when the patient needs gastroscopy “ride” sampling, microscopic examination together with biopsy sampling. Detection of the presence of H. pylori. If positive, the diagnosis of positive H. pylori infection can be confirmed. Bacterial culture and drug sensitivity testing can sometimes be added in order to develop an appropriate treatment plan for the patient. Gastroscopic sampling can also be followed by polymerase chain reaction (PCR) testing, which is more sensitive and has more reliable results, or rapid urease testing, which is easy and fast, but the results are less reliable due to the short observation time or the influence of certain factors. Gastroscopy sampling also has the following problems: patients need to undergo gastroscopy, and if H. pylori is focally distributed it is easy to lead to a missed diagnosis (the rate of missed diagnosis is about 10%). However, with the doctor’s extensive experience and proper sampling, the leakage rate can be reduced. 3, breath sampling test The test sensitivity, detection rate and compliance rate is also very high, and the patient is painless, is one of the most popular methods of detecting H. pylori in recent years. 14C urea breath test is less expensive (generally 80-100 yuan), no damage to the human body, easy, good compliance, and high detection rate and compliance rate (more than 95%). The 14C breath test has been recognized as the best method for detecting H. pylori.