Clinical gastroenterology clinic about half of the gastrointestinal disease patients are functional gastrointestinal disease, but due to the doctor and the patient’s lack of understanding of the disease, delayed treatment of the best time. Part of the long-term treatment of chronic gastritis, aggravated the condition. So what is functional gastrointestinal disease? Functional gastrointestinal disease is a complex interaction of physiological, mental, psychological and social factors that produce a functional digestive system syndrome. Mental and psychological factors play an important role in the development of functional gastrointestinal diseases, which not only affects the physiology of the stomach and intestines, but also affects the patient’s symptomatic experience, disease behavior, choice of treatment options and prognosis. In recent years, the proposed biopsychosocial model of the disease has led to a deeper understanding of the disease. Functional gastrointestinal disorder (FGID) is a group of symptom clusters with chronic and recurrent GI symptoms without structural and biochemical abnormalities. With the development of society and the acceleration of the pace of life, the stress originating from society, work and life increases, and psychosomatic diseases are increasingly receiving widespread attention. A survey of 5,430 families in the United States found that 69% had at least one functional gastrointestinal syndrome in the past 3 months according to the Rome Diagnostic Criteria. Analyzed by anatomical site, 42% had esophageal disorders, 26% had gastric and duodenal disorders, 44% had intestinal disorders, and 26% had anorectal disorders. In a recent survey of 1,149 people in Canada according to the Rome II criteria, it was found that 61.7% had at least one functional gastrointestinal disorder (FGID), with functional bowel disorders being the most prevalent at 41.6%, followed by esophageal disorders at 28.9%. The high prevalence of FGID has a serious impact on physical and psychological well-being, quality of work and life, and greatly increases health care expenditures. The transformation of the medical model of morbidity from a simplified biological model to an integrated biopsychosocial model15 and the introduction of the concept of brain-gut interactions have led to an increased awareness, understanding, and concern about FGID, especially with regard to the importance of psychological abnormalities and social stress in the development and progression of the disease. The importance of psychological abnormalities and social stress in the occurrence and development of the disease has been greatly emphasized. Heart disease must also be treated. Several common functional gastrointestinal disorders: 1. Irritable bowel syndrome (IBS) Using Manning’s criteria and Rome’s criteria II to survey the population of Beijing, the prevalence of IBS was 7.26% and 0.82%. IBS has a close relationship with psychiatric and psychological factors, and 54-100% of IBS suffer from psychiatric and psychological abnormalities; most of them are impaired by a depressive state, anxiety, and an impaired mode of adaptation. Non-cardiogenic chest pain, esophageal dyskinesia and unexplained vomiting have been shown to be associated with panic disorder.It has been found that 46.3 % of 41 patients suffering from panic disorder were compatible with the diagnosis of IBS.Patients with IBS have increased rectal sensitivity and significant psychological problems such as obsessive-compulsive disorder, depression and anxiety. In addition, psychological and behavioral factors play an important role in the perception of pain in patients with IBS, and a regression analysis found that psychological and behavioral factors related to acquired illness behaviors were key determinants of IBS symptom severity, but less than half of patients with IBS sought treatment for their illness, and 50-90% of these patients had psychiatric disorders, including panic disorder, anxiety, social phobia, post-traumatic stress disorder, and major depression. Functional dyspepsia (FD) FD is also a common functional disorder, with a reported prevalence of 18-45% in China. Its onset is related to gastric tolerance dysfunction and gastrointestinal motility disorders, and is also closely related to psychosomatic factors. Gastroesophageal reflux disease (GERD), functional esophageal chest pain (FECP), functional abdominal pain (FAP), and so on, are associated with different degrees of mental and psychological abnormalities, such as anxiety, depression, panic disorder, and somatization disorder. In addition, FGID has personality traits such as neurohypersensitivity, and its personality traits affect the outcome of antidepressant treatment. Many studies have shown that psychosocial treatment, such as cognitive-behavioral therapy, hypnotherapy, biofeedback therapy, and relaxation therapy are effective in improving the symptoms of IBS.Hamilton et al treated 39 patients with chronic refractory FD with a psychodynamic approach, and their psychometric assessments improved significantly compared with those of the control group after treatment, and their symptoms remained improved at follow-up of After the treatment, their psychological assessment improved significantly compared with the control group, and the improvement of their symptoms was still maintained at 12 months of follow-up. Biofeedback and habit training were used to treat 100 women with intractable constipation for 12-48 months, with significant results, and 60% of the patients were able to maintain the long-term effects, as well as improve their mental health and quality of life. It has been shown that the treatment of idiopathic constipation by biofeedback is achieved by increasing the activity of brain innervation of the gastrointestinal tract and improving gastrointestinal transit. Heymann-Monnikes’ treatment of patients with IBS using conventional medication and multifaceted behavioral therapy resulted in significant improvements in clinical symptoms, quality of life, and perception of their own well-being when compared to the control group treated with conventional medication alone; at the third and sixth months of follow-up, their clinical symptoms and quality of life improved significantly. months 3 and 6, their clinical symptoms still continued to be relieved. In conclusion, FGID is a typical disease of biopsychosocial medical model, and mental and psychological factors, stress and life events are closely related to the development of FGID, and all kinds of external information through the brain-intestinal axis affects gastrointestinal motility and sensation at different levels, and at the same time, the somatic reaction further affects human emotions and behaviors. The treatment of FGID should address the different levels of the brain-gut axis and adopt the principles of integrated and individualized treatment, so good communication with the doctor is fundamental to the treatment.