Highly differentiated squamous cell carcinoma can be cured. Squamous cell carcinoma is generally categorized into low-differentiated, middle-differentiated and high-differentiated, especially in the early stage of high-differentiated squamous cell carcinoma, most of the patients can be cured through radical surgical resection treatment. Most of the patients with highly differentiated squamous cell carcinoma can be cured through active treatment. Highly differentiated squamous cell carcinoma proves that the cancer is well differentiated and less malignant. However, the treatment effect needs to be decided according to the specific site of disease, stage, age, physical condition and other factors. Patients with highly differentiated squamous cell carcinoma can usually be cured through radical surgical resection and usually have a better prognosis, and can also be treated with radiotherapy after surgery to promote recovery. However, there is a risk of recurrence, and patients should go to the hospital regularly for follow-up and testing of their condition. If you experience any discomfort or abnormal symptoms, you should go to the hospital in time for treatment, and do not use medication on your own.