Cold legs and knee pain is recommended to first brake rest, reduce the activities of the knee, appropriate warmth, local hot compresses, physiotherapy and drug treatment. Knee pain after catching a cold is mostly caused by the wear and tear of the knee over a long period of time. The following treatments are recommended when the knee gets cold: First, brake and rest, reduce the activity of the knee, pay attention to keep warm. Local hot compresses, physiotherapy or ultrasound treatment can be used to relieve symptoms. You can use local medicines to activate blood circulation and remove blood stasis such as Yunnan Baiyao and Panax ginseng tablets or non-steroidal anti-inflammatory drugs such as indomethacin and rofecoxib to treat the condition. In addition, for patients with knee pain after long-term leg cold, it is recommended to consult a doctor in a timely manner, complete the relevant imaging examination, and carry out targeted treatment after clarifying the extent of joint lesions. The above drugs need to be standardized and reasonably used under the guidance of professional physicians and pharmacists.