Gamma-glutamyltransferase is an indicator of liver function and is one of the markers of liver impairment.High gamma-glutamyltransferase may be due to physiologic or pathologic causes. It can be treated with drugs such as glutathione. 1. Physiological reasons: If you drink alcohol, stay up late, overwork before the examination, it will increase the burden on the liver and lead to a mild increase in glutamyl transferase. Usually there will be no obvious symptoms and no serious harm to the body. Usually after removing the triggers and taking sufficient rest, the glutamyl transferase will return to the normal level. It can be treated with drugs such as Zoxorubicin. 2. Pathological causes: If γ-glutamyltransferase is high due to bile duct stones, biliary tract tumors and other diseases, surgery can be used to remove the biliary tract obstruction. It can be restored to normal level by relieving biliary obstruction or removing tumors surgically, or treating biliary stones through endoscopic choledochotomy and lithotripsy. It can be treated with drugs such as glutathione and compound glycyrrhizin tablets. Patients with viral hepatitis may have elevated gamma-glutamyl transpeptidase, and patients need to avoid drinking alcohol and take drugs such as interferon and lamivudine for treatment if necessary. For patients who drink a lot of alcohol for a long time, glutamyl transpeptidase will be significantly elevated. These patients should strictly abstain from alcohol, and at the same time adopt liver-protecting drugs such as reduced glutathione and silymarin capsules. Patients who feel unwell need to go to the hospital as soon as possible to confirm the diagnosis, under the guidance of the doctor’s instructions for standardized treatment. Pay attention to rest, ensure sufficient sleep, eat more apples, pears and other vitamin-rich fruits.