As a result of long-distance travel by train or on foot, venous reflux in the lower extremities and sagging upper extremities is restricted due to gravity, which increases the hydrostatic pressure in the capillaries and causes body fluid to seep and accumulate in the subcutaneous tissue spaces. Swelling of the lower extremities may occur, which is medically known as traveler’s edema. Therefore, do not always sit when riding in a car, you should always change your position, or stand for a while or elevate the lower limbs to sit for a while, or use your hands to massage the lower limbs from top to bottom to help blood flow back. What is the prevention of edema in travelers? Don’t always sit in the car, change your position, stand for a while or sit with your lower limbs elevated, or massage your lower limbs from top to bottom to help blood flow back. If the edema is strong, the salt intake can be appropriately limited, and water does not necessarily need to be strictly controlled. When the edema is significant, a small amount of dihydrocotrimoxazole can be used, 25mg (1 tablet) each time twice a day for three days, and the edema can subside. Traveler’s edema is a condition in which the patient may experience swelling of the lower extremities because of gravity after long hours of hitchhiking, walking, standing, etc. If you suffer from traveler’s edema, you can drink salt water appropriately and avoid prolonged standing and walking. Traveler’s edema can be recovered in 2 to 3 days by stopping travel and does not need to be treated with medication. Sometimes salt intake can be appropriately restricted, and water does not necessarily need to be strictly controlled. When edema is significant, a small amount of dihydrocotrimoxazole can be used, 25mg (1 tablet) each time twice a day, and the edema can subside after taking it for several days.