Right lower limb L4-S1 paravertebral muscle neurogenic damage refers to the transverse striated muscle trophic disorder, its muscle fibers become thin, and in severe cases, it will disappear, after the onset of the disease can be treated by physical, drug, surgery and other methods. 1. Physical methods: right lower limb L4-S1 paravertebral muscle neurogenic injury, its muscle strength is weakened, so it is necessary to increase the exercise of muscle strength, such as walking training can exercise muscle strength, but also enhance the body’s resistance to disease, and ultimately alleviate the patient’s muscle fiber thinning and other manifestations. 2. Drug therapy: for patients with a longer course of the disease, it is easy to produce muscle weakness, muscle atrophy, and can not work normally, this situation needs to be given to the patient’s medication, follow the doctor’s instructions to use disodium adenosine triphosphate tablets, ethylpiperidone hydrochloride tablets, standardized medication can promote the health of the damaged muscle neuron restoration, to alleviate the muscle weakness and other discomforts. 3. Surgery: For patients with severe symptoms and indications for surgery, surgery is feasible. After the right lower limb L4-S1 paravertebral muscle nerve source damage, its treatment time should not be delayed, need to go to the regular hospital immediately.