An arterial plaque thickness of 2 millimeters is not serious in itself, but if it is combined with cardiovascular and cerebrovascular diseases or other underlying diseases, the severity of the condition will increase significantly. Arterial plaque thickness of 2 mm suggests that arterial vessels have begun to develop atherosclerosis, which leads to a decrease in the elasticity of blood vessels and even to the development of closed stenosis, leading to ischemia of vital organs. An arterial plaque of 2 millimeters alone does not cause serious consequences and the condition is not serious. Patients with arterial plaque 2 mm should pay attention to the examination of vital organs to find out whether the patient’s heart, brain and kidneys are damaged. If there is a combination of damage to the heart, brain, kidneys and other organs, the severity of the condition will increase significantly, and there is a risk of cardio-vascular and cerebrovascular acute complications at any time. Patients with arterial plaque should be careful to control various risk factors and be treated under the guidance of a physician to avoid serious complications.