Chemotherapy for liver metastasis of pancreatic head cancer may be useful, and commonly used drugs include oxaliplatin, gemcitabine, etc. Radiation therapy and other treatments are also available. Pancreatic head cancer is a kind of digestive tract tumor, which is highly malignant and easy to metastasize. Usually, chemotherapy for pancreatic head cancer liver metastasis has certain therapeutic effect, which is a commonly used method to kill tumor cells in clinic and can effectively inhibit tumor growth. For liver metastasis of pancreatic head cancer, chemotherapy drugs commonly used in clinic include oxaliplatin, gemcitabine, irinotecan, albumin paclitaxel and so on. In addition to chemotherapy, patients with pancreatic head cancer liver metastasis may need radiotherapy at this time, which can reduce the chance of local recurrence to a certain extent. At the same time, interventional therapy is also needed to help the chemotherapeutic drugs act on the tumor area. The prognosis of this disease is poor, and patients need to actively cooperate with doctors for treatment. To summarize, pancreatic head cancer is a chronic consumptive disease, once diagnosed, patients need to treat it in time, strengthen daily life management, and review on time.