A woman’s legs and feet swelling in the afternoon may be caused by hypothyroidism, chronic glomerulonephritis, right heart failure. 1. Hypothyroidism. Women with hypothyroidism have a lot of mucopolysaccharides due to a decrease in thyroid hormone levels in the body and a slowing down of the body’s metabolism. Mucopolysaccharides are hydrophilic and tend to combine with fluids in the body, causing non-concaveable edema. Under the effect of gravity, swelling of legs and feet in the afternoon may occur. 2. Chronic glomerulonephritis. Chronic glomerulonephritis will cause a decrease in the filtration function of the kidneys, and the water in the body can not be effectively excreted through the kidneys, resulting in water and sodium retention, and the phenomenon of body edema. If female patients are standing or walking for a long time in the afternoon, it will cause poor blood circulation in the lower limbs, so it will lead to swelling of the legs and feet. 3. Right heart failure. Right heart failure of female patients in the afternoon legs and feet swelling, may also be due to right heart failure resulting in increased pressure in the venous system, high pressure in the body circulation, while under the effect of gravity, causing leg and foot edema. There are many other reasons for women to have swollen legs and feet in the afternoon, it is recommended to consult a doctor in a timely manner to clarify the cause, and follow the doctor’s instructions for treatment, do not take medication without authorization, so as not to cause adverse consequences.