Hand skin roughness in winter is considered to be related to age factor, eczema, vitamin deficiency, tinea versicolor and other factors. It is recommended to take good local care, detach from the environment, supplement nutritional elements, and give antihistamine, glucocorticoid and antifungal drugs. 1. Age factor: with age, the skin may gradually aging, resulting in rough skin. It is recommended to reduce adverse stimuli and pay attention to hand moisturizing. 2. Eczema: frequent contact with washing powder, soap, detergent, disinfectant, lime, cement, decoration materials, motor oil, etc., long-term chronic stimulation leading to hand allergy, skin keratinization and chapping. It is recommended to detach from the environment, reduce the contact of the above substances, wear gloves when necessary, and apply topical urea ointment and hydrocortisone butyrate cream for treatment. 3. Vitamin A deficiency: Vitamin A deficiency can cause dryness and roughness of the skin and mucous membranes, and night blindness in some patients. It is recommended to pay attention to the balance of nutrition, eat more food containing vitamin A, and supplement a variety of trace elements if necessary. 4. Ringworm: ringworm is caused by fungal infection, such as scaly keratosis pilaris, mainly manifested as skin thickening, roughness, dryness, flaking and so on. You can use compound benzoic acid ointment, terbinafine hydrochloride ointment, bifonazole cream and so on to apply treatment. Rough skin on the hands in winter is considered to be related to a variety of factors. It is recommended to reduce the adverse stimuli, if necessary, go to the hospital dermatology department for diagnosis and treatment.