Sore and watery eyes may be caused by visual fatigue, allergic conjunctivitis, dacryocystitis, etc. General measures, medication, and surgical treatment should be taken to address the specific causes. 1. Visual fatigue: common symptoms include dry eyes, sore eyes, blurred vision and tearing. Patients need to close their eyes and let them rest, or use hot towels to apply warm compresses to improve local blood circulation. If necessary, you need to follow the doctor’s instructions to apply artificial tears, seven leaves of digitalis glycoside eye drops or nafamivir eye drops and other drugs, can play a role in anti-fatigue, relieve discomfort. 2. Allergic conjunctivitis: Typical symptoms are itching, burning sensation, photophobia, eyelid swelling, tearing and so on. Patients need to get rid of allergens, good personal protection, the eye can be iced. Patients need to follow the doctor’s instructions to apply emetine, levocabastine and other antihistamine eye drops, or orotidine, ketotifen and other antihistamines and mast cell stabilizers dual-action drugs. For patients with severe disease and corneal epithelial defects, surgical treatment such as bandage lens and amniotic membrane covering may need to be considered. 3. Dacryocystitis: the main symptoms are eye swelling, pain, tearing and so on. In the early stage, localized hot compresses or ultrashort wave physiotherapy can be used. Patients need to follow the doctor’s instructions to apply sulfasalazine, sulfadiazine and other antibiotics, or levofloxacin, ofloxacin and other antibiotics eye drops. For those with abscesses, incision and drainage are required; for those with acute dacryocystitis in remission and those with chronic dacryocystitis, nasal lacrimal sac anastomosis is required. It is recommended that patients with sore, swollen and watery eyes go to the hospital and actively treat the primary disease.