Segmental motion abnormalities of the left ventricular wall are abnormal left ventricular wall movements that suggest a weakening or loss of localized motion of the left ventricle of the heart. Segmental motion abnormalities of the left ventricular wall can interfere with the patient’s normal breathing, resulting in shortness of breath. When it causes insufficient blood supply to the myocardium, it may contribute to a decrease in myocardial contractility, and segmental necrosis of the ventricular wall may be detected on examination. Segmental motion abnormalities of the left ventricular wall are usually seen in patients who have had a myocardial infarction, or who have had an old myocardial infarction. As soon as possible after diagnosis, oral antiplatelet aggregating drugs, such as aspirin, should be administered; when there is coronary artery stenosis, nitroglycerin should be combined with vasodilator therapy. Stent implantation is recommended if drug therapy is not effective. Segmental motion abnormalities of the left ventricular wall may also be due to left bundle branch block or pericardial adhesions. It is recommended to consult a doctor in time after the discovery of the abnormality, and analyze the cause under the guidance of a professional physician before treating the symptoms.