The throat feels uncomfortable to breathe, mainly seen in the following cases: 1. A more common clinical disease is acute epiglottitis. Patients with acute epiglottitis suffer from inspiratory dyspnea and pharyngeal discomfort, mostly with sore throat as the main manifestation, and severe patients can also have clinical manifestations such as trigeminal signs. Once this disease appears, patients are advised to go to the ENT department as soon as possible for anti-inflammatory intravenous infusion therapy, hormone intravenous infusion therapy, supplemented by nebulization therapy, and patients are advised to be hospitalized. 2. Some patients have edematous pharyngitis and also experience respiratory discomfort. This condition may be due to the patient’s allergic reaction to food, medication, and localized diffuse edema of the pharynx. Such a patient may also feel inspiratory dyspnea in the oropharynx. In conclusion, patients who feel a little uncomfortable breathing in the throat are advised to go to the Department of Otolaryngology as soon as possible for an oropharyngeal and laryngopharyngeal examination.