Lung nodule 4 x 2.4cm presenting with pain may be a more serious condition. It is recommended that the patient should go to the hospital in time for review and examination of chest CT scan, tumor marker test, tuberculin skin test, etc. to clarify the cause of the disease. Lung nodule 4 x 2.4cm with pain is a more serious condition, which may be caused by the rapid growth of the tumor or the involvement of tuberculosis foci in the pleura or chest wall. The patient may also be accompanied by symptoms such as cough, dyspnea, hemoptysis, malaise and low fever. Patients are advised to go to the hospital in time to check the benign or malignant nature of the tumor. Chest X-ray, chest CT scan, tumor marker test, tuberculin skin test and other tests can be performed to clarify the diagnosis. If it is malignant nodules should be treated in time to avoid delay.