Sertraline generally refers to sertraline hydrochloride tablets and causing diarrhea may be a side effect of the drug. Sertraline hydrochloride tablets are commonly used clinically for the treatment of psychosis. During the administration of this drug, it may affect the normal digestion and absorption function of the gastrointestinal tract, resulting in clinical symptoms such as diarrhea, abdominal distension, nausea and vomiting. Generally speaking, the symptoms can disappear on their own after stopping taking this drug, so there is no need to worry too much. During the period of taking sertraline should pay attention to, first of all, it is recommended that it is best to take this drug half an hour after meals to reduce the stimulation of the gastrointestinal tract, to avoid the occurrence of gastrointestinal adverse reactions. During the use of the drug should pay attention to try to maintain a light diet, do not eat greasy spicy stimulating food, do not increase the burden of digestion and absorption of the gastrointestinal tract. If you need to use the drug, please consult a professional physician, the occurrence of obvious adverse reactions, stop the drug in time to seek medical attention.