Painful growths on the side of the knee are mainly due to degeneration of the knee joint, with gradual wear and tear of the cartilage and the gradual formation of calcification and growths around it. This can cause irritation to the surrounding soft tissues and can lead to pain in the lateral aspect of the knee. First, use hormones and local anesthetics mixed in the local closed injection, commonly used drugs are prednisone acetate injection and lidocaine hydrochloride injection, can effectively control the local inflammation stimulation, reduce the pain symptoms. Second, the knee joint must be relaxed and rested as much as possible, avoiding continued strenuous exercise or long-distance travel activities, which may lead to an increase in local hyperplasia, and may also lead to hyperplasia and aggravation of the surrounding tissue stimulation. Thirdly, we must pay attention to the warmth of the knee joint in general and not to get cold, because cold will certainly lead to an increase in local pain symptoms.