In Chinese medicine, thyroid nodules belong to the category of “gall disease”, and the treatment of the disease needs to recognize the evidence, and commonly used formulas include Sihai Shuyu Pill, Seaweed Yuhu Tang and so on. 1. Qi depression and phlegm obstruction: the patient’s neck is enlarged and soft, with no pain when pressed, and the condition is related to fluctuations in emotions and moods; the patient’s pulse is stringy, and the moss is thin and white. To regulate qi and resolve phlegm (regulating the body’s qi to resolve phlegm), the commonly used formula is Sihai Shuyu Pill plus subtractions. 2. Phlegm and blood stasis: the patient has a lump in the neck, which is hard when pressed, with a stringy pulse and whitish moss. Resolving phlegm and activating blood circulation is the mainstay, and Seaweed Yuhu Tang plus subtractions can be used. 3. Excessive liver fire: the patient has swelling in the front of the neck, irritability and sweating, protruding eyeballs, red tongue, thin yellow moss, and stringy pulse. To clear the liver and cathartic fire (clear liver fire) mainly. Commonly used formula is Gardenia Liver Cleansing Soup combined with Algae Medicinal Powder plus reduction. The adverse reactions and contraindications of the above formula are not clear. If there is any discomfort, it is recommended to consult a doctor in time, and it should be used by a traditional Chinese medicine practitioner after diagnosis, avoiding self-medication, so as to avoid adverse consequences.