Possible causes of peri-shoulder pain include inflammation, strain, trauma, etc. Mild peri-shoulder pain may heal on its own without treatment, while severe peri-shoulder pain requires prompt treatment. If the pain around the shoulder is mild, the main cause may be short-term bad sitting habits, work, strenuous exercise, etc. By correcting the bad sitting posture, reducing the time of work, regular exercise, etc., generally without special treatment, the pain in the shoulder can be significantly relieved, but you need to pay attention to the maintenance of good sitting habits and exercise habits. Severe shoulder pain is mostly caused by muscle soft tissue inflammation, rotator cuff tear, rheumatoid arthritis, bursitis, etc., and needs to be treated according to the cause. For example, severe pain requires the use of non-steroidal anti-inflammatory drugs such as celecoxib for pain relief and anti-inflammation; rheumatoid arthritis requires the use of methotrexate, etc.; and in severe cases, even surgical treatment is required. All of the above drugs may have side effects such as gastrointestinal discomfort. If you have pain in the periapical region, it is recommended that you go to a regular hospital to find out the cause of the pain, and then take active treatment, rather than blindly using medication.