Anesthesia overdose is divided into general anesthetic overdose and local anesthetic overdose. General anesthetic overdose may cause respiratory depression, resulting in hypoventilation and hypoxia, as well as circulatory depression leading to hypotension or, in more severe cases, cardiac arrest. There is also a risk of delayed awakening, especially in elderly patients or those with hepatic or renal insufficiency and obese patients. This is because these patients take longer to metabolize general anesthetic drugs. Local anesthetic overdose may result in local anesthetic toxicity, causing various clinical signs of excitation or depression of the patient’s central nervous system and cardiovascular system. In mild cases, dizziness and ringing in the ears may occur and generally do not require treatment. If convulsions, convulsions or even cardiac and respiratory arrest occur in severe cases, active resuscitation must be performed. At present, with the improvement of the level of anesthesiologists, it is possible to use the characteristics of various anesthetic drugs for compounding, and the phenomenon of anesthetic overdose is becoming less and less common.