The most fundamental and major cause of diabetes is the decline of pancreatic islet B-cell function, which is caused by insufficient insulin secretion. When the blood glucose level just reaches the diagnostic standard of diabetes, the pancreatic islet B-cell function has already declined by more than 50%. Protecting and delaying the decay of islet B-cell function is an important strategy for diabetes treatment. Therefore, insulin is the most effective magic weapon in diabetes treatment. However, many people worry that insulin injection will make them dependent on insulin, or even become hidden or long-term insulin injection will lead to lazy dependence. Is it so? The answer is no! Firstly, exogenous insulin treatment for diabetes can reduce the secretion of endogenous insulin, thus reducing the burden of pancreatic B cells, which is conducive to protecting pancreatic B cells and delaying its decay, and pancreatic B cell function can also be restored to a certain extent. Therefore insulin treatment for diabetes not only will not lead to insulin dependence, but also can reduce the dose of oral hypoglycemic drugs applied alone. So it is even less likely to become hidden. Secondly, will long-term insulin injection therapy lead to wasting hypofunction of pancreatic B cells or called lazy dependence. The answer is no. Insulin treatment for diabetes mimics physiological insulin secretion and can only be a partial replacement and cannot exceed the physiological requirement, otherwise it will lead to hypoglycemia. Blood sugar will also not stabilize at an ideal level without moving. A normal person’s fasting blood sugar is around 5mmol/L and below 8mmol/L after meals. Although 7~8mmol/L does not exceed our prescribed postprandial blood sugar level, it is high for the body’s internal environment and more insulin has to be used to lower the blood sugar to below 6mmol/L. That means blood glucose 7~8mmol/L will stimulate insulin secretion by pancreatic B cells, and the dose of insulin we inject is mainly to supplement the insufficient part or slightly more, and it is impossible for pancreatic B cells to rest completely. Therefore it will not lead to lazy dependence. At the current medical level, insulin treatment for diabetes is the most powerful magic weapon. Please feel free to use it for diabetic patients. Short-term insulin intensive therapy for 2-3 months for early type 2 diabetic patients can induce the recovery of pancreatic B-cell function, and then can be changed to non-insulin therapy. In some patients, after intensive insulin therapy, not only insulin but even all medications can be discontinued, and diet and exercise control alone can bring blood glucose to or near normal levels! However, most patients with long duration of disease have serious loss of pancreatic B-cell function due to long-term oral treatment with certain drugs, and just like a resource that is exhausted and must be imported from other countries, they must also and have to receive insulin replacement therapy for a long time. Choosing insulin long-term treatment at an early stage, this can delay the decay of pancreatic B-cells and contribute to long-term blood sugar stability. Of course diabetes treatment is a complex process. The good or bad blood sugar control is related to the disease itself, but also to diet, exercise, emotion, good or bad program and many other factors. The medication is not the more expensive or the more the better. You should be guided by a professional endocrinologist. May all my diabetic friends be healthy and live happily!