The statement that major triple-positive is hepatitis B is not accurate enough; it should be said that a major triple-positive is a person with hepatitis B or a carrier of the hepatitis B virus. A patient with hepatitis B, in addition to the major triple-positive status, may also be a minor triple-positive or minor di-positive. If there are also clinical symptoms or liver function abnormalities, such as elevated glutamic aminotransferase and glutamic oxalacetic aminotransferase or bilirubin, the patient is a hepatitis B patient, and if there are no clinical symptoms or liver function abnormalities, the patient is a hepatitis B virus carrier. The difference between patients with major triple yang and other states is that the level of hepatitis B virus DNA in the body is higher, which is because the hepatitis B virus in the body is more actively replicating. When the replication is active, the body will express an antigen called E antigen, while the E antibody will not be expressed, so it will show the state of major triple-positive. In contrast to small triple-positive patients, small triple-positive patients are negative for E antigen and positive for E antibody because the virus is not actively replicating, which is different from large triple-positive patients.