Low back pain and numbness of legs are usually caused by lesions in the lumbar region such as lumbar disc herniation, lumbar spinal stenosis, etc. Generally, you can take some nutritive nerve medications, non-steroidal anti-inflammatory drugs, myorelaxants and so on, and the medications should be taken under the guidance of the doctor, and should not be used blindly in order to avoid any adverse reactions. 1. Nutritional nerve drugs: such as methylcobalamin, adenosylcobalamin, etc., can help reduce the edema of the nerve roots and relieve the symptoms of lumbago and leg numbness. 2. Non-steroidal anti-inflammatory drugs: such as ibuprofen, diclofenac sodium, etc. By inhibiting the synthesis of prostaglandins, eliminating the local aseptic inflammation, reducing the inflammatory factor, and alleviating the symptoms of low back pain and numbness of legs. 3. muscarinic drugs: such as ethopiridone, etc., can reduce the tension and spasm of the lumbar muscles and reduce the symptoms of lumbar pain. The symptoms of lumbago and leg numbness should be timely to the hospital, improve the relevant examination, clear diagnosis and standardized treatment in accordance with the doctor’s instructions, do not blindly use their own medication, so as not to delay the condition.