Waking up in the morning with swollen hands may be caused by prolonged compression of the upper limbs, or it may be caused by osteoarthritis, rheumatoid arthritis, as well as other causes such as tenosynovitis of the fingers. 1. Prolonged compression of the upper extremities: sleeping for a long time compression of the upper extremities will affect the upper extremity blood circulation and lymphatic circulation, may appear in the morning woke up swollen hands performance. 2. Osteoarthritis: the cause of osteoarthritis is still unclear, and it is considered to be related to congenital joint deformity, joint injury, joint instability and other factors. Osteoarthritis will be manifested as joint pain, limited joint movement, joint enlargement, etc. Osteoarthritis in the finger area will show the symptom of swollen hands when waking up in the morning. 3. Rheumatoid arthritis: the cause of rheumatoid arthritis is not yet clear, and it is considered to be related to heredity, infection, smoking and other factors. Patients will have swollen joints, pain, morning stiffness and other manifestations, and will wake up in the morning with swollen hands. 4. Others: It may also be caused by finger tenosynovitis, rheumatoid arthritis, hypoproteinemia, heart disease, kidney disease and other causes. If the symptoms continue to be unrelieved, you should go to the hospital in time, and standardize the treatment under the guidance of the doctor.