HIV viral load is not detectable in the blood often indicates that the patient is not significantly infectious, the patient only needs to adhere to long-term antiviral treatment, and in the process of treatment regularly review, each review viral load can be less than 20copies/ml, that is, the virus does not occur drug resistance, this situation patients basically no infectious. Of course, this is not absolute, because the HIV virus belongs to the RNA virus, in the process of replication is very easy to mutate, once the virus mutation can appear virological breakthrough, the virus can appear positive again, so regardless of whether the patient’s viral load can be detected should be careful, positive treatment, to adhere to take antiviral drugs, adhere to the regular review of viral load, if there is drug resistance to If drug resistance occurs, change the drug in time for treatment.