Severe mitral regurgitation without surgery may lead to cardiac insufficiency, causing serious complications such as heart failure, dyspnea, arrhythmia, and in severe cases may even be life-threatening, so it needs to be treated as soon as possible. The mitral valve is a one-way valve between the left ventricle and the left atrium, which serves to prevent blood from flowing backward into the left atrium during left ventricular systole. Minor regurgitation will not have many consequences, but if severe regurgitation occurs, it can easily lead to insufficient ejection of blood during ejection, and cardiac insufficiency, causing heart failure. At the same time, serious complications such as dyspnea, lower limb edema, jugular vein varicose and so on may occur, which may seriously affect the quality of daily life of the patients. At the same time, a large amount of mitral regurgitation may lead to compensatory enlargement of the heart under the long-term effect, which affects the electrophysiology of the heart, and arrhythmia occurs, which may even lead to the sudden death of the patients in serious cases. Therefore, people with severe mitral regurgitation need to go to the hospital for early and timely treatment, mainly surgical treatment to effectively improve symptoms, avoid complications, increase quality of life and prolong life as much as possible.