Taking cephalexin and drinking cola will not cause poisoning. Because cola does not contain alcohol, it will not cause poisoning symptoms. However, the ingredients in cola may affect the absorption of cephalosporin and reduce the efficacy of cephalosporin. It is not recommended to drink cola when taking cephalosporin, and it is better to drink warm boiled water to take it. During taking cephalosporin, one should not drink drinks containing alcohol because cephalosporin can affect the metabolism of alcohol and cause bisulfite-like reaction. Patients mainly show chest tightness, shortness of breath, laryngeal edema, difficulty in breathing, accelerated heart rate, decreased blood pressure, headache, nausea and vomiting, etc. Severe anaphylactic shock can occur. During the period of taking cephalosporin, not only should one not drink drinks containing alcohol, but also within one week of stopping the medicine. If the patient develops the above symptoms while taking cephalosporin, it is recommended to go to the hospital for medical treatment and diagnosis in time to avoid delaying the disease.