Tuberculosis usually does not cause symptoms of hot and cold spells, but also cold and hot spells when high fever occurs in severe patients. Common clinical manifestations of TB include cough, sputum, blood in sputum, weight loss, fatigue, night sweats, and prolonged afternoon low-grade fever. Tuberculosis will cause the patient’s body temperature to rise in the afternoon or evening, but it is usually low fever, which will cause hot flashes on the patient’s cheeks, palms, feet and other parts of the body. When tuberculosis dissemination occurs, patients with symptoms of tuberculosis poisoning, tuberculosis mycobacteria replication is active, the human body temperature often rises significantly, high fever will lead to the patient to produce chills, hot and cold and other symptoms. In addition, other germs invade the respiratory tract, urinary tract and other parts of the body when infection occurs, will also make the body fever and produce symptoms of hot and cold. After the symptoms of chills and fever should go to the hospital in a timely manner, improve the examination to clarify the cause of the disease and then give targeted treatment.