Marfon syndrome is also known as congenital mesodermal dysplasia, Marchesani syndrome, spider’s finger syndrome, and limb slenderness. It is characterized by peripheral connective tissue dystrophy, skeletal abnormalities, internal eye disease, and cardiovascular abnormalities, and is a genetic disorder in which connective tissue is the underlying defect. Wandering kidney is one of the concomitant symptoms of equine Fang syndrome, why does it occur? The cause: It is an autosomal dominant disorder with some autosomal recessive inheritance, the exact cause is unknown, and it is thought to be related to congenital abnormal protein metabolism. dietz et al. (1991) identified the gene for the disease as 15q15 to q21.3 by chain analysis of families. in many tissues of the body such as endocardium, heart valves, large blood vessels, and bones, there are chondroitin sulfate Abraham et al. (1982) suggested that abnormalities in aortic elastin, a decrease in pontine and isopontine proteins, and a corresponding increase in lysyl residues are the main changes in the disease. Patients have increased urinary hydroxyproline excretion and increased blood mucin and mucopolysaccharide. It is an autosomal dominant disorder that can be inherited from either parent and has a prevalence of about 50% in their children.