The old saying goes, “Wine is a poison, color is a steel knife to scrape the bones, money is downhill tiger, gas is the root of the trouble.” It must have a reason, so where is the reason? Many people are quite unconvinced that “wine is a poison to the intestines”. The history of wine is also ancient and modern, a long history, it can be said that wine throughout the history of human civilization, should not be a problem. Many people say that wine is not poisonous, is the essence of grain, wine to promote blood circulation has certain health benefits, wine can improve the mood and atmosphere, and so on. So is wine poisonous or not. The main component of wine is alcohol, the scientific name of ethanol, is the product of fermentation and metabolism of mycobacteria. As we all know, many antimicrobials are metabolites of various molds, natural molds secrete a variety of bactericidal and antibacterial substances (i.e. antibiotics), in order to destroy bacteria and other nutrient-depleting competitors in their own extended periphery. Alcohol is a relatively simple molecular structure, with the same effect, to kill inhibit the surrounding bacteria substances. It is for this reason that alcohol solutions can be used as disinfection in life and in medicine. So the synthesis of alcohol is born to be used as a weapon to inhibit other microorganisms and is toxic. Alcohol is not an essential nutrient, and no living creature can survive without it. Even if it produces euphoria, it is still harmful to the human body, except that each person can tolerate different doses. The history of such things began to be treated as a treasure, let people float, and later proved to be a drug is not less. Initially wine is the grains of pure grain brewing, is pure grain solid fermented liquor, with mellow quality and immortal cultural flavor. Later, in order to save food, reduce costs, people use sugar cane, beet residue, corn, potatoes, groundnuts to create alcohol, and then mixed with wine lees steamed with spices, the production of wine looks similar, but its taste is poor, containing a large number of toxic substances. At this point, please judge for yourself if the wine is toxic and harmful to your body. The poisonous effects of wine on the liver. After absorbed by the gastrointestinal tract, wine is converted into acetaldehyde in the liver by the action of ethanol dehydrogenase, which then generates acetic acid and finally decomposes into carbon dioxide and water and is discharged from the body. But when you drink too much alcohol, the acetaldehyde in your body is too late to be transformed into acetic acid, which is highly toxic and generates a large number of superoxide anion free radicals, and you will become drunk or alcoholic. The body will become intoxicated or alcoholic. This will cause greater harm to the body over time. People who drink too much alcohol over a long period of time will develop a fatty liver, with an enlarged liver, hardened texture, yellow color, and loss of normal function. Every healthy adult has the ability to break down and digest alcohol, but each person’s ability to detoxify alcohol varies depending on their genetic predisposition, whether they drink frequently, their age, and their health and psychological condition at the time of drinking. In general, the higher the alcoholic strength of the wine, the lower the amount of alcohol should be, the total amount of alcohol in a day, white wine should generally be controlled at about 50 ml, yellow wine can be in about 100 ml, red wine control in 150-200 ml, beer control in about 500 ml is appropriate. Drinking must be measured, a small amount of alcohol, may promote blood circulation and have certain health benefits. Excessive drinking, damage to the body, the benefits become side effects, it is not worth the loss.