Multiple myeloma creatinine 300μmol/L needs chemotherapy, avoiding the application of renal injury drugs, correcting dehydration, controlling hypercalcemia and hyperuricemia, and dialysis treatment if necessary.
Multiple myeloma is prone to cause kidney injury, which increases creatinine, at this time the treatment first needs to be based on the multiple myeloma situation for the appropriate chemotherapy program treatment.
For kidney involvement, firstly, it is necessary to avoid applying drugs that have damage to kidney, such as contrast agents, non-steroidal anti-inflammatory drugs, aminoglycoside antibiotics such as streptomycin, etc. Secondly, it is necessary to correct dehydration, control hypercalcemia, hyperuricemia, etc., to adequately hydrate and alkalinize the urine, and to reduce the formation of tubular, and the commonly used drugs include saline, zoledronic acid and so on.
If creatinine continues to rise or hypercalcemia occurs, hemodialysis treatment is needed.
Patients with elevated creatinine in multiple myeloma need individualized treatment under the guidance of a specialist and according to the patient’s individual situation.