The use of retinoic acid cream pores bigger may be caused by overdose, need to promptly adjust the dose of medicine. Vitamin A cream belongs to the dermatology commonly used drugs, clinically used for acne, blackheads, pimples, skin atrophy, all kinds of keratosis pilaris and psoriasis treatment. If the dose of the drug is too high, it may cause the skin to appear larger pores. Topical use of the drug is likely to cause skin irritation and other adverse reactions such as burning sensation, red rashes and flakes, which can make the lesions worse. Pregnant women in the third trimester of pregnancy, lactating women, patients allergic to the product avoid using the drug, and also note that the drug is contraindicated for use in the eyes. When using the drug, patients are advised to pay attention to the correct way of using the drug, and avoid using other drugs or cleansers that are prone to cause skin irritation or breakage, or else it will easily lead to skin damage and other side effects appear. The use of Vitamin A acid should be carried out under the guidance of a doctor, if there is any discomfort after using the drug, go to the hospital in time for examination and treatment.