Aspartate aminotransferase, also known as glutamate aminotransferase, is mainly distributed in cardiac muscle cells, followed by liver, skeletal muscle and kidney and other tissues. High aspartate aminotransferase suggests the following possibilities: a. Physiological causes: frequent late nights, long-term insomnia, strenuous exercise, prolonged walking and other non-disease causes can lead to transient elevation of serum aspartate aminotransferase, and after removing the above-mentioned triggers, it can self After removing the above triggers, it can return to normal. Pathological causes: 1. Myocardial infarction: Since aspartate aminotransferase mainly exists in cardiac muscle cells, when myocardial infarction occurs, the enzyme will be rapidly released into the blood and will reach its peak in 24 hours; 2. Liver damage: aspartate aminotransferase can be elevated due to various causes of liver damage. It is usually accompanied by elevated alanine aminotransferase. For example, fatty liver, viral hepatitis, alcoholic liver damage, drug-related liver damage, autoimmune liver disease, cholangitis, cholecystitis, EBV infection, cytomegalovirus infection, liver abscess, liver schistosomiasis, schistosomiasis, etc.; 3, other diseases: aspartate aminotransferase also exists in the pancreas, muscle, lymph and other tissues, and damage or lesions in these organs can also cause aspartate aminotransferase to rise. Aspartate aminotransferase is also found in the pancreas, muscle, lymph and other tissues. The aspartate aminotransferase is elevated because of many reasons, so you need to go to the hospital in time to clarify the cause and then take treatment measures according to the cause to avoid delaying the disease.